The Pennsylvania Railroad ended up using the greatest number (598) of 2-10-0 locomotives. They were quite successfully used on the PRR Allegheny Mountain routes.
Because of the lack of a rear truck, the 2-10-0 wheel arrangement meant that the firebox be place between the drives making it very narrow or on top of the drivers making it very high and shallow also limiting the driver diameter. As a result, these locomotives could only be used for slow drag service.
| No. | Class | F.M. Whyte | Gauge | Railroad Line | Location | Status | Builder Info | Notes |
|---|---|---|---|---|---|---|---|---|
| 1615 | Russian | 2-10-0 | 4'-8½" | SLSF | Missile Park, Altus, OK | display | Baldwin #58829, 1917 | |
| 950 (600) | G | 2-10-0 | 4'-8½" | MSP&SSM (Buffalo & Susquehanna) | near depot, Ashland, WI | display | Baldwin #17914, 1900 | |
| 1632 | Russian | 2-10-0 | 4'-8½" | SLSF (Southern) | Belton Grandview & Kansas City Railroad, Belton, MO | restoration | Baldwin #48522, 1918 | Cosmetic restoration only. |
| 203 (402) | D-2 | 2-10-0 | 4'-8½" | GM (AT&N) | Southeastern Railway Museum, Duluth, GA | stored | Baldwin #60342, 1928 | |
| 1625 | Russian | 2-10-0 | 4'-8½" | SLSF | Museum of the American Railroad, Frisco, TX | display | Alco (Schenectady) #58903, 1918 | |
| 209 (533) | D-2 | 2-10-0 | 4'-8½" | GM (SAL) | park, Gainesville, GA | display | Baldwin #61233, 1930 | |
| 4483 | I1sa | 2-10-0 | 4'-8½" | PRR | Western NY Railway Hist Soc, Hamburg, NY | display | Baldwin #56534, 1923 | Possible candidate for restoration to operation with the proper funding. May be moved to the Heritage Discovery Center. |
| 544 (206) | Russian | 2-10-0 | 4'-8½" | SAL (GM) | North Carolina Transportation Museum, Spencer, NC | display | Alco (Brooks) #58902, 1918 | |
| 1621 | Russian | 2-10-0 | 4'-8½" | SLSF | Museum of Transportation, St. Louis, MO | display | Baldwin #48420, 1918 | |
| 90 | 12-42-F | 2-10-0 | 4'-8½" | Strasburg (GWR) | Strasburg Railroad, Strasburg, PA | out of service | Baldwin #57812, 1924 | One of only two 2-10-0 type steam locomotives in operation in the USA, the other one being Frisco 1630 at the Illinois Railway Museum, Union, IL. Taken out of service in December 2023. Undergoing mandated 1,472-day inspection and overhaul. |
| 41 (401) | 12-42-F | 2-10-0 | 4'-8½" | Woodward Iron (AT&N) | Age of Steam Roundhouse, Sugarcreek, OH | display | Baldwin #60341, 1928 | Sold to Georgia Car & Loco Co. in 1946; sold to Woodward Iron Co. in 1948; sold to Mid-Continent RR Museum in 1964. |
| 1630 | Russian | 2-10-0 | 4'-8½" | SLSF | Illinois Railway Museum, Union, IL | operational | Baldwin #47953, 1918 | Appeared in 'A League of Their Own'. One of only two 2-10-0 type steam locomotives in operation in the USA, the other one being Great Western 90 at the Strasburg Railroad. Previously operated in 2004. Restored back to operation in late October 2013. |
| 208 (530) | D-2 | 2-10-0 | 4'-8½" | GM (SAL) | Winder Chamber of Commerce, Winder, GA | display | Baldwin #61230, 1930 |